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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABL2 All Species: 39.39
Human Site: S546 Identified Species: 78.79
UniProt: P42684 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42684 NP_001093578.1 1182 128343 S546 F E T M F H D S S I S E E V A
Chimpanzee Pan troglodytes XP_001156169 1182 128389 S546 F E T M F H D S S I S E E V A
Rhesus Macaque Macaca mulatta XP_001115453 1182 128030 S546 F E T M F H D S S I S E E V A
Dog Lupus familis XP_537174 1169 126779 S533 F E T M F H D S S I S E E V A
Cat Felis silvestris
Mouse Mus musculus Q4JIM5 1182 128178 S546 F E T M F H D S S I S E E V A
Rat Rattus norvegicus NP_001100656 1208 131452 S544 F E T M F H D S S I S E E V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515903 1140 123564 S509 F E T M F H D S S I S E E V A
Chicken Gallus gallus XP_422269 1134 124028 S509 F E T M F H D S S I S E E V A
Frog Xenopus laevis NP_001084399 1102 120702 L506 C P P K V Y E L M R A C W Q W
Zebra Danio Brachydanio rerio NP_001116177 1135 123693 S504 F E T M F H D S S I S E E V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P00522 1620 171570 S629 L E H M F Q E S S I T E A V E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P03949 1224 138308 N569 L E N L I S S N S L N D E V Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 96.3 94.2 N.A. 94.6 89.3 N.A. 84.4 83.6 70.8 68 N.A. 34.8 N.A. 32.1 N.A.
Protein Similarity: 100 99.8 97.7 94.9 N.A. 96 90.7 N.A. 88.2 87.5 79 76 N.A. 46.4 N.A. 48.4 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 0 100 N.A. 53.3 N.A. 26.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 20 100 N.A. 66.6 N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 9 0 9 0 75 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 0 0 0 0 0 75 0 0 0 0 9 0 0 0 % D
% Glu: 0 92 0 0 0 0 17 0 0 0 0 84 84 0 9 % E
% Phe: 75 0 0 0 84 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 9 0 0 75 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 84 0 0 0 0 0 % I
% Lys: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 17 0 0 9 0 0 0 9 0 9 0 0 0 0 0 % L
% Met: 0 0 0 84 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 9 0 0 9 0 0 0 0 % N
% Pro: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 9 0 0 0 0 0 0 0 9 9 % Q
% Arg: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 9 9 84 92 0 75 0 0 0 0 % S
% Thr: 0 0 75 0 0 0 0 0 0 0 9 0 0 0 0 % T
% Val: 0 0 0 0 9 0 0 0 0 0 0 0 0 92 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _